New Information on Lyrica, a Medication Used for Fibromyalgia Treatment and Not Only

Brasov, Romania, March 10, 2010 -- Pain medication has evolved over ages of scientific research and discovery and today, many diseases which were associated with severe, unbearable pain have been made manageable by these medicines.

Pregabalin or Lyrica, as it is popularly known, is an anticonvulsant drug, used to treat a variety of diseases associated with pain or convulsions. Epilepsy, Fibromyalgia, Post herpetic neuralgia and Diabetic neuropathy pain – are some of the conditions known to be treated by this drug. Prescribed only to Adults, it is a drug that has been approved in the USA and the European Union as an effective therapy for seizures and neuropathic pain. It is sold by the leading pharmaceutical company Pfizer. Read up more on the history of the drug and its research on www.lyricamedication.info

Pain in human body is registered by the brain, the message of ‘pain’ being carried by the numerous neurons of the nervous system. A hypersensitive neuron causes a seizure or severe pain and Pregabalin acts on this mechanism of neurons. The alpha2- subunits present in the dorsal horn of the spinal cord and the brain, release calcium units, which regulate the flow of neurons. Pregabalin soothes this site, in turn regulating the flow of hyper-sensitive neurons and effectively reducing or managing pain.

When ingested, Lyrica makes its effect felt in the body in three different steps namely Absorption, distribution, and metabolism. Lyrica is always prescribed for oral consumption and advice to be taken on an empty stomach. Its absorption is said to be the highest when the stomach is empty, while it takes time to be absorbed if consumed along with food. It is then distributed around the body by the blood stream, many a times breaking within the body – for instance the placenta, of a growing baby in the womb, or breast milk of a lactating mother. Finally it undergoes some metabolic changes, which are insignificant in the human body. The residue is then excreted by the kidneys through urine.

Being a drug which controls the neurons of the body, it should be taken under strict medical approval and guidance. It is known to be very potent and the patient is always advised to take it smaller doses to begin with. This gives the body time to build up for its potency, and this also ensures little or no side effects. Though it is usually advised to be taken on an empty stomach to ensure quicker absorption, many patients complain of nausea or dizziness if taken that way. It can be then be consumed with meals. This is not proven to reduce its effectiveness. While slowly increasing the dosage, the patient reaches the optimum dose prescribed to him or her, it is then important to maintain regularity in consuming the medicine. It is usually prescribed to be taken twice or thrice a day. It is best taken at the same time every day – though one should be careful of not overdosing. If a single dose has been missed, one can take it as soon as they remember to, but making sure it is not too close to the next one. If two doses are taken too close to each other, it may cause an overdose causing drowsiness, fatigue and nausea. The extent of symptoms will depend on the potency of overdose. A detailed source of information on the drug can be found at www.lyricamedication.info

If taken for pain relief from Fibromyalgia or other neurological disorder resulting in pain, the dosage is different from what it is when prescribed to treat Epilepsy or seizures. For pain management, the patient is usually prescribed a 50 mg of dosage, spread over two or three doses per day. This is slowly increased to a maximum of three doses of 100 mg each, in a single day. Any more than that, is considered an overdose, which will not relieve pain but adversely affect the body in uncomfortable symptoms like dizziness, fatigue and nausea – all associated with an overdose of the drug.

If taken for epilepsy and its symptoms, the dosage is higher. Starting with a dose of 75mg, it is increased to 150 mg to 600 mg per day. The higher limit of 600 mg is prescribed only to patients exhibiting severe symptoms and is very rare. As and when the body is worked up to accept higher doses of the drug, the doctor watches the patient closely for any adverse side effects and the dosage is altered accordingly.

With a drug so potent, one needs to be aware of possible side effects and practice caution while consuming it. Lyrica is known to have side effects, which include dizziness, nausea and fatigue – which usually affect patients in the first few weeks of starting the medicine. While the body gets used to the new chemical in the body and the changes it manifest, these side effects also disappear. You should definitely inform your doctor is side effects are severe, including palpitations or chest pains, eye pain, tiredness, muscle fatigue along with fever, or vision changes and even, hallucinations. Pregnant women and lactating women should inform the physician accordingly, for this drug is known to enter the blood stream of the embryo and in breast milk. It should also not be taken along with alcohol. When reducing doses or stopping the medicine all together, the doctors’ advice is imperative. This is because it is known to cause withdrawal symptoms if body is declined of it abruptly.

This drug has proven to be very effective for patients suffering from neurological pain and epilepsy. Taken with care, it can be a powerful tool of pain management and a successful anticonvulsant.
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